metcardio.org
 Meta-analysis and Evidence-based Medicine Training in Cardiology
The metcardio.org website is dedicated to meta-analysis and evidence-based medicine training in cardiology. It is sponsored by the Meta-analysis and Evidence-based medicine Training in Cardiology (METCARDIO) Group, currently headquartered in Turin, Italy, and formerly known as the Center for Overview, Meta-analysis, and Evidence-based Medicine Training (COMET). The focus of the metcardio.org website is on clinical research methods and evidence-based cardiovascular medicine with a specific interest in interventional cardiology and peripheral cardiovascular interventions. Nonetheless, there is plenty of training and research opportunities for other evidence-based endeavors, eg in anesthesiology, critical care medicine, and psychiatry.


Title: Incidedence and predictors of coronary stent thrombosis: evidence from an international collaborative meta-analysis
Highlights: Clinical studies reporting on the incidence and predictors of coronary stent thrombosis in the drug-eluting stent era will be systematically searched, appraised and pooled with meta-analytic methods
Search strategy: PubMed will be searched for pertinent articles published between January 2002 (when DES were first marketed worldwide) and July 2010 according to the following highly sensitive strategy, in keeping with established methods and incorporating wild cards (identified by *): stent* AND thrombosis AND coronary AND english[lang] AND ("2002"[pdat] : "3000"[pdat]) NOT (review[pt] OR editorial[pt] OR letter[pt]). All corresponding authors of shortlisted studies were directly emailed for further data and suggestions for additional studies
Principal investigator: Fabrizio D'Ascenzo, University of Turin, Turin, Italy

Title: Right versus left radial artery access for coronary procedures: a systematic review and meta-analysis of randomized trials
Search strategy: PubMed will be searched for pertinent articles in keeping with established methods and incorporating wild cards (identified by *): right AND left AND (radial OR ulnar) AND coronary AND (randomized controlled trial[pt] OR controlled clinical trial[pt] OR randomized controlled trials[mh] OR random allocation[mh] OR double-blind method[mh] OR single-blind method[mh] OR clinical trial[pt] OR clinical trials[mh] OR (clinical trial[tw] OR ((singl*[tw] OR doubl*[tw] OR trebl*[tw] OR tripl*[tw]) AND (mask*[tw] OR blind[tw])) OR (latin square[tw]) OR placebos[mh] OR placebo*[tw] OR random*[tw] OR research design[mh:noexp] OR follow-up studies[mh] OR prospective studies[mh] OR cross-over studies[mh] OR control*[tw] OR prospectiv*[tw] OR volunteer*[tw]) NOT (animal[mh] NOT human[mh]) NOT (comment[pt] OR editorial[pt] OR meta-analysis[pt] OR practice-guideline[pt] OR review[pt])) stent* AND thrombosis AND coronary AND english[lang] AND ("2002"[pdat] : "3000"[pdat]) NOT (review[pt] OR editorial[pt] OR letter[pt])
Principal investigator: Giuseppe Biondi-Zoccai, University of Modena and Reggio Emilia, Modena, Italy

Title: Comparative effectiveness of novel oral anticoagulants for non-valvular atrial fibrillation: evidence from a warfarin-controlled network meta-analysis
Search strategy: PubMed will be searched for pertinent articles in keeping with established methods and incorporating wild cards (identified by *): apixaban OR rivaroxaban OR dabigatran OR (novel AND oral AND anticoagulant*)) AND atrial AND fibrillation AND (randomized controlled trial[pt] OR controlled clinical trial[pt] OR randomized controlled trials[mh] OR random allocation[mh] OR double-blind method[mh] OR single-blind method[mh] OR clinical trial[pt] OR clinical trials[mh] OR (clinical trial[tw] OR ((singl*[tw] OR doubl*[tw] OR trebl*[tw] OR tripl*[tw]) AND (mask*[tw] OR blind[tw])) OR (latin square[tw]) OR placebos[mh] OR placebo*[tw] OR random*[tw] OR research design[mh:noexp] OR follow-up studies[mh] OR prospective studies[mh] OR cross-over studies[mh] OR control*[tw] OR prospectiv*[tw] OR volunteer*[tw]) NOT (animal[mh] NOT human[mh]) NOT (comment[pt] OR editorial[pt] OR meta-analysis[pt] OR practice-guideline[pt] OR review[pt]))
Principal investigator: Giuseppe Biondi-Zoccai, University of Modena and Reggio Emilia, Modena, Italy